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Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Jianrong Liu , Aurelie Maisonial-Besset , Barbara Wenzel , Damien Canitrot , Ariane Baufond , et al.
European Journal of Medicinal Chemistry, 2017, 136, pp.548 - 560. ⟨10.1016/j.ejmech.2017.03.091⟩
Journal articles hal-01671041v1
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Bis-14-membered ring diketal diamines: Synthesis and evaluation of their anti-HIV and anti-tumoral activities.

Radouane Affani , Franck Pélissier , Anne-Marie Aubertin , Denise Dugat
European Journal of Medicinal Chemistry, 2009, 44, epub ahead of print. ⟨10.1016/j.ejmech.2009.03.008⟩
Journal articles hal-00384465v1
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Improved potency of pyridin-2(1H)one derivatives for the treatment of mechanical allodynia

Alexia Visseq , Amélie Descheemaeker , Karine Hérault , Francis Giraud , Isabelle Abrunhosa-Thomas , et al.
European Journal of Medicinal Chemistry, 2021, 225, pp.113748. ⟨10.1016/j.ejmech.2021.113748⟩
Journal articles hal-03334145v1
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Synthesis and biological activities of aminopyrimidyl-indoles structurally related to meridianins

Rufine Akué-Gédu , Eric Debiton , Yoan Ferandin , Laurent Meijer , Michelle Prudhomme , et al.
Bioorganic and Medicinal Chemistry, 2009, 17, pp.4420-4424
Journal articles hal-00392799v1
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Synthesis and biological evaluation of diversely substituted indolin-2-ones

Fadoua Bouchikhi , Emilie Rossignol , Martine Sancelme , Bettina Aboab , Fabrice Anizon , et al.
European Journal of Medicinal Chemistry, 2008, 43, pp.2316-2322
Journal articles hal-00333575v2
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Stereoselective Synthesis of Fluorinated Galactopyranosides as Potential Molecular Probes for Galactophilic Proteins: Assessment of Monofluorogalactoside–LecA Interactions

Vincent Denavit , Danny Lainé , Chahrazed Bouzriba , Elena Shanina , Emilie Gillon , et al.
Chemistry - A European Journal, 2019, 25 (17), pp.4478-4490. ⟨10.1002/chem.201806197⟩
Journal articles hal-02104563v1
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A Novel HPLC Method for Direct Detection of Nitric Oxide Scavengers from Complex Plant Matrices and Its Application to Aloysia triphylla Leaves

Didier Fraisse , Alexandra Degerine-Roussel , Alexis Bred , Samba Ndoye , Magali Vivier , et al.
Molecules, 2018, 23 (7), pp.1574. ⟨10.3390/molecules23071574⟩
Journal articles hal-01873226v1
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A Photochemical Approach to Pyridopyrroloquinoline Derivatives as New Potential Anticancer Agents

Pierre-Jean Aragon , Ange-Désiré Yapi , Frédéric Pinguet , Jean-Michel Chezal , Jean-Claude Teulade , et al.
Chemical and Pharmaceutical Bulletin, 2004, 52, pp.659 - 663. ⟨10.1248/cpb.52.659⟩
Journal articles hal-02384520v1
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Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

Damien Lanfray , Sébastien Arthaud , Johanne Ouellet , Vincent Compère , Jean-Luc Do Rego , et al.
Diabetes, 2013, 62 (3), pp.801-810. ⟨10.2337/db11-0785⟩
Journal articles hal-01962799v1
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Benefits of the ipowder® extraction process applied to Melissa officinalis L.: improvement of antioxidant activity and in vitro gastro-intestinal release profile of rosmarinic acid

Valérie Bardot , Anaïs Escalon , Isabelle Ripoche , Sylvain Denis , Monique Alric , et al.
Food and Function, 2020, 11 (1), pp.722-729. ⟨10.1039/c9fo01144g⟩
Journal articles hal-02441644v1
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A proof of principle study using radiopharmaceuticals to quantify and localize container-content interactions in medical syringes

C. Dupire , P. Chennell , B. Pereira , N. Courtiol , S. Buj , et al.
Scientific Reports, 2023, 13 (1), pp.2721. ⟨10.1038/s41598-023-29923-z⟩
Journal articles hal-04144593v1
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Synthesis and biological evaluation of Haspin inhibitors: kinase inhibitory potency and cellular activity

Wael Zeinyeh , Yannick Esvan , Béatrice Josselin , Mathilde Defois , Blandine Baratte , et al.
European Journal of Medicinal Chemistry, 2022, 236, pp.114369. ⟨10.1016/j.ejmech.2022.114369⟩
Journal articles hal-03764791v1
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Heteropolysaccharides from S. cerevisiae show anti-adhesive properties against E. coli associated with Crohn’s disease

Adeline Sivignon , Shin-Yi Yu , Nathalie Ballet , Pascal Vandekerckove , Nicolas Barnich , et al.
Carbohydrate Polymers, In press, 271, pp.118415. ⟨10.1016/j.carbpol.2021.118415⟩
Journal articles hal-03373401v1
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Effect of proteases against biofilms of Staphylococcus aureus and Staphylococcus epidermidis

Pierre-Henri Elchinger , C. Delattre , S. Faure , O. Roy , S. Badel , et al.
Letters in Applied Microbiology, 2014, 59 (5), pp.507-513. ⟨10.1111/lam.12305⟩
Journal articles hal-01081362v1
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Metabolic and Anti-Inflammatory Protective Properties of Human Enriched Serum Following Artichoke Leaf Extract Absorption: Results from an Innovative Ex Vivo Clinical Trial

Fabien Wauquier , Line Boutin-Wittrant , Aurélien Viret , Laure Guilhaudis , Hassan Oulyadi , et al.
Nutrients, 2021, 13 (8), pp.2653. ⟨10.3390/nu13082653⟩
Journal articles hal-03326084v1
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Pharmacological characterization of (4R)-alkyl glutamate analogues at the ionotropic glutamate receptors - Focus on subtypes iGluR5-7

Lennart Bunch , Thierry Gefflaut , Sébastien Alaux , Emmanuelle Sagot , Brigitte Nielsen , et al.
European Journal of Pharmacology, 2009, 609, pp.1-4
Journal articles hal-00376953v1
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Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of pyrrolo[3,4-a]carbazole-1,3-diones, pyrrolo[3,4-c]carbazole-1,3-diones, and 2-aminopyridazino[3,4-a]pyrrolo[3,4-c]carbazole-1,3,4,7-tetraone

Elisabeth Conchon , Fabrice Anizon , Bettina Aboab , Roy Golsteyn , Stéphane Leonce , et al.
European Journal of Medicinal Chemistry, 2008, 43, pp.282-292
Journal articles hal-00255899v1
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Chemo-enzymatic synthesis of a series of 2,4-syn-functionalized (S)-glutamate analogues: new insight into the structure-activity relation of ionotropic glutamate receptor subtypes 5, 6, and 7.

Emmanuelle Sagot , Darryl S. Pickering , Xiasui Pu , Michelle Umberti , Tine B. Stensbol , et al.
Journal of Medicinal Chemistry, 2008, 51, pp.4093-4103
Journal articles hal-00323861v1
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Current Opinion on Chitosan and its Derivatives: Biological Impact in Antimicrobial Applications From Nature to Chitosan and It Derivatives: How it is Working?

Cédric Delattre
Advances in Biotechnology & Microbiology, 2017, 6 (2), ⟨10.19080/AIBM.2017.06.555684⟩
Journal articles hal-01657856v1
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Synthesis and biological evaluation of new dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4,6-tetraones, substituted with various saturated and unsaturated side chains via palladium catalyzed cross-coupling reactions

Hélène Henon , Fabrice Anizon , Roy Golsteyn , Stéphane Leonce , Robert Hofmann , et al.
Bioorganic and Medicinal Chemistry, 2006, 14, pp.3825-3834. ⟨10.1016/j.bmc.2006.01.030⟩
Journal articles hal-00023499v1
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Synthesis and in Vitro Cytotoxic Evaluation of New Derivatives of Pyrido[1,2-a]benzimidazolic Ring System: The Pyrido[1,2:1,2]imidazo[4,5-h]quinazolines

Marianne Dupuy , Frédéric Pinguet , Olivier Chavignon , Jean-Michel Chezal , Jean-Claude Teulade , et al.
Chemical and Pharmaceutical Bulletin, 2001, 49, pp.1061 - 1065. ⟨10.1248/cpb.49.1061⟩
Journal articles hal-02384513v1
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Chemo-enzymatic synthesis of (2S,4R)-2-amino-4-(3-(2,2-diphenylethylamino)-3 oxopropyl)pentanedioic acid: A novel Selective inhibitor of human excitatory amino acid transporter subtype 2

Emmanuelle Sagot , Anders A. Jensen , Darryl S. Pickering , Xiasui Pu , Michelle Umberti , et al.
Journal of Medicinal Chemistry, 2008, 51, pp.4085-4092
Journal articles hal-00323786v1
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A three-step synthesis from rebeccamycin of an efficient checkpoint kinase 1 inhibitor.

Fabrice Anizon , Roy Golsteyn , Stéphane Leonce , Bruno Pfeiffer , Michelle Prudhomme
European Journal of Medicinal Chemistry, 2009, 44, pp.2234-2238
Journal articles hal-00371170v1
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Development of a new radiofluorinated quinoline analog for PET imaging of phosphodiesterase 5 (PDE5) in brain

Jianrong Liu , Barbara Wenzel , Sladjana Dukic-Stefanovic , Rodrigo Teodoro , Friedrich-Alexander Ludwig , et al.
Pharmaceuticals, 2016, 9 (2), pp.22. ⟨10.3390/ph9020022⟩
Journal articles hal-01677542v1
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Synthesis and Biological Evaluation of Indoloquinolines and Pyridocarbazoles: A New Example of Unexpected Photoreduction Accompanying Photocyclization

Pierre-Jean Aragon , Ange-Désiré Yapi , Frédéric Pinguet , Jean-Michel Chezal , Jean-Claude Teulade , et al.
Chemical and Pharmaceutical Bulletin, 2007, 55 (9), pp.1349-1355. ⟨10.1248/cpb.55.1349⟩
Journal articles hal-02384499v1
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Neuroprotective Effects of a Novel Demeclocycline Derivative Lacking Antibiotic Activity: From a Hit to a Promising Lead Compound

Rodrigo Tomas-Grau , Florencia González-Lizárraga , Diego Ploper , César Avila , Sergio Socías , et al.
Cells, 2022, 11 (17), pp.2759. ⟨10.3390/cells11172759⟩
Journal articles hal-03775634v1
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Advances in tetrahydropyrido[1,2-a]isoindolone (valmerins) series: Potent glycogen synthase kinase 3 and cyclin dependent kinase 5 inhibitors.

Rajâa Boulahjar , Aziz Ouach , Stéphane Bourg , Pascal Bonnet , Olivier Lozach , et al.
European Journal of Medicinal Chemistry, 2015, 101, pp.274-287. ⟨10.1016/j.ejmech.2015.06.046⟩
Journal articles hal-01212495v1
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Quick and Simple Detection Technique to Assess the Binding of Antimicrotubule Agents to the Colchicine-Binding Site

Sébastien Fortin , Jacques Lacroix , Marie-France Côté , Emmanuel Moreau , Éric Petitclerc , et al.
Biological Procedures Online, 2010, 12 (1), pp.113-117. ⟨10.1007/s12575-010-9029-5⟩
Journal articles hal-01677569v1
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Azoliums and Ag(I)‐N‐Heterocyclic Carbene Thioglycosides: Synthesis, Reactivity and Bioactivity

Dmytro Ryzhakov , Audrey Beillard , Franck Le Bideau , Riyadh Ahmed Atto Al‐shuaeeb , Mouad Alami , et al.
European Journal of Organic Chemistry, 2022, 2022 (9), pp.e202101499. ⟨10.1002/ejoc.202101499⟩
Journal articles hal-03648181v2
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Synthesis, chekpoint kinase 1 inhibitory properties and in vitro antiproliferative activities of new pyrrolocarbazoles

Elisabeth Conchon , Fabrice Anizon , Bettina Aboab , Roy Golsteyn , Stéphane Leonce , et al.
Bioorganic and Medicinal Chemistry, 2008, 16, pp.4419-4430
Journal articles hal-00277522v1