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Journal Articles Journal of Organic Chemistry Year : 2015

Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines

Abstract

Pseudo-three-component reactions are de- scribed for the conversion of simple N-aryl imines into 1,2- dihydroisoquinoline-type products. The approach relies on a regioselective cascade reaction involving two equivalents of the aryne component iteratively as a dienophile and as an electrophile. Some examples of related, more complex pseudo-four-component cascade processes are also reported.
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Dates and versions

hal-01224324 , version 1 (04-11-2015)

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Juan-Carlos Castillo, Jairo Quiroga, Rodrigo Abonia, Jean Rodriguez, Yoann Coquerel. Pseudo-Multicomponent Reactions of Arynes with N-Aryl Imines. Journal of Organic Chemistry, 2015, 80, pp.9767. ⟨10.1021/acs.joc.5b01564⟩. ⟨hal-01224324⟩
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