MicroRNAs in Obesity and Related Metabolic Disorders - Aix-Marseille Université Access content directly
Journal Articles Cells Year : 2019

MicroRNAs in Obesity and Related Metabolic Disorders

Abstract

Metabolic disorders are characterized by the inability to properly use and/or store energy. The burdens of metabolic disease, such as obesity or diabetes, are believed to arise through a complex interplay between genetics and epigenetics predisposition, environment and nutrition. Therefore, understanding the molecular mechanisms for the onset of metabolic disease will provide new insights for prevention and treatment. There is growing concern about the dysregulation of micro-RNAs (miRNAs) in metabolic diseases. MiRNAs are short non-coding RNA molecules that post-transcriptionally repress the expression of genes by binding to untranslated regions and coding sequences of the target mRNAs. This review aims to provide recent data about the potential involvement of miRNAs in metabolic diseases, particularly obesity and type 2 diabetes.
Fichier principal
Vignette du fichier
cells-08-00859.pdf (795.91 Ko) Télécharger le fichier
Origin Publisher files allowed on an open archive
Loading...

Dates and versions

hal-02487569 , version 1 (21-02-2020)

Licence

Identifiers

Cite

Jean-Francois Landrier, Adel Derghal, Lourdes Mounien. MicroRNAs in Obesity and Related Metabolic Disorders. Cells, 2019, 8 (8), pp.859. ⟨10.3390/cells8080859⟩. ⟨hal-02487569⟩
26 View
90 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More