Enantiospecific Generation and Trapping Reactions of Aryne Atropisomers - Aix-Marseille Université Access content directly
Journal Articles Journal of the American Chemical Society Year : 2020

Enantiospecific Generation and Trapping Reactions of Aryne Atropisomers

Abstract

Enantioenriched aryne atropisomers having a biaryl stereogenic axis vicinal to the reactive triple bond are demonstrated to exist. These reaction intermediates are easily produced in situ and can undergo the standard aryne cycloaddition chemistry in an enantiospecific manner. Notably, the aryne atropisomers herein have allowed the practical syntheses of a small nanographene as well as some triptycene and anthracene derivatives that embed stereogenic axes of controlled absolute configurations.
Fichier principal
Vignette du fichier
pub-2020JACS-16921bis.pdf (990.59 Ko) Télécharger le fichier
Origin Files produced by the author(s)
Loading...

Dates and versions

hal-02990635 , version 1 (05-11-2020)

Identifiers

Cite

Yun-Long Wei, Guillaume Dauvergne, Jean Rodriguez, Yoann Coquerel. Enantiospecific Generation and Trapping Reactions of Aryne Atropisomers. Journal of the American Chemical Society, 2020, 142 (40), pp.16921-16925. ⟨10.1021/jacs.0c08218⟩. ⟨hal-02990635⟩

Relations

33 View
81 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More