Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo
Abstract
Probing the polarity of spontaneous perisomatic GABAergic synaptic transmission in the mouse CA3 circuit in vivo Graphical abstract Highlights d CA3 PV-interneurons generate perisomatic unitary GABAergic field potentials in vivo d GABAergic unitary fields can be used to probe inhibition with single-cell resolution d GABA reversal after acute seizures is restricted to the postictal silent period d GABAergic excitation during KA epileptogenesis is restricted to 0.6% of CA3 neurons
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