7T Epilepsy Task Force Consensus Recommendations on the Use of 7T MRI in Clinical Practice - Aix-Marseille Université Access content directly
Journal Articles Neurology Year : 2021

7T Epilepsy Task Force Consensus Recommendations on the Use of 7T MRI in Clinical Practice

1 Neurobiology Research Unit, Department of Neurology Rigshospitalet Copenhagen University Hospital, UCPH
2 Faculty of Health and Medical Sciences, UCPH
3 Utrecht Brain Center [UMC]
4 Department of Radiology University Medical Center Utrecht
5 Skane University Hospital [Lund]
6 Department of Neurology Neurophysiology and Neurosurgery, ACE Kempenhaeghe/MUMC, Heeze/Maastricht
7 PENN Epilepsy Center
8 Department of Neurology University of Minnesota, Minneapolis
9 Department of Radiology and Nuclear Medicine Maastricht University Medical Center
10 MHeNs - School for Mental Health and Neuroscience [Maastricht]
11 Imaging Institute [Cleveland]
12 Department of Neurology and Radiology University of Pittsburg
13 Medizinische Universität Wien = Medical University of Vienna
14 Department of Radiology Hospital of the University of Pennsylvania, Philadelphia
15 CMRR - Center for Magnetic Resonance Research [Minneapolis]
16 Neuroradiology Division, Diagnostic Unit University Hospitals and Faculty of Medicine of Geneva
17 Epilepsy Center Cleveland Clinic
18 INS - Institut de Neurosciences des Systèmes
19 Service de neurophysiologie clinique [Hôpital de la Timone - APHM]
20 MNI - McConnell Brain Imaging Centre
21 GU - Göteborgs Universitet = University of Gothenburg
22 Department of Translational Research on New Technologies in Medicine and Surgery
23 Department of Neurology University of Pennsylvania, Philadelphia
24 BAOBAB - Building large instruments for neuroimaging: from population imaging to ultra-high magnetic fields
25 EEG Section, NINDS, NIH, Bethesda
26 UWO - University of Western Ontario
27 Imaging Research Laboratories, Robarts Research Institute, London
28 Functional Neurosurgery Department Beijing Children's Hospital of Capital Medical University, Beijing
29 Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston
30 Epilepsy Clinic, Department of Neurology, Rigshospitalet Copenhagen University Hospital
31 Harvard-MIT Division of Health Sciences and Technology [Cambridge]
32 Athinoula A. Martinos Center for Biomedical Imaging
33 CRMBM - Centre de résonance magnétique biologique et médicale
34 CEMEREM - Centre d'Exploration Métabolique par Résonance Magnétique [Hôpital de la Timone - APHM]
35 Scannexus Ultrahigh Field MRI Research Center, Maastricht
36 Department of Radiology and Nuclear Medicine Meander Medical Center, Amersfoort
37 LRMN - Laboratoire d'Imagerie et de Spectroscopie
38 WIN - FMRIB - Wellcome Trust Centre for Integrative Neuroimaging
39 UNIGE - Université de Genève = University of Geneva
40 BNU - Beijing Normal University
41 UniFI - Università degli Studi di Firenze = University of Florence = Université de Florence
42 IMAGO 7 Foundation, Florence
Irene Wang
Boris Bernhardt
Sara Inati
Michael Jurkiewicz
Heath Pardoe


Identifying a structural brain lesion on MRI has important implications in epilepsy and is the most important factor that correlates with seizure freedom after surgery in patients with drug-resistant focal onset epilepsy. However, at conventional magnetic field strengths (1.5 and 3T), only approximately 60%–85% of MRI examinations reveal such lesions. Over the last decade, studies have demonstrated the added value of 7T MRI in patients with and without known epileptogenic lesions from 1.5 and/or 3T. However, translation of 7T MRI to clinical practice is still challenging, particularly in centers new to 7T, and there is a need for practical recommendations on targeted use of 7T MRI in the clinical management of patients with epilepsy. The 7T Epilepsy Task Force—an international group representing 21 7T MRI centers with experience from scanning over 2,000 patients with epilepsy—would hereby like to share its experience with the neurology community regarding the appropriate clinical indications, patient selection and preparation, acquisition protocols and setup, technical challenges, and radiologic guidelines for 7T MRI in patients with epilepsy. This article mainly addresses structural imaging; in addition, it presents multiple nonstructural MRI techniques that benefit from 7T and hold promise as future directions in epilepsy. Answering to the increased availability of 7T MRI as an approved tool for diagnostic purposes, this article aims to provide guidance on clinical 7T MRI epilepsy management by giving recommendations on referral, suitable 7T MRI protocols, and image interpretation.



Dates and versions

hal-03501353 , version 1 (23-12-2021)



Giske Opheim, Anja van Der Kolk, Karin Markenroth Bloch, Albert Colon, Kathryn Davis, et al.. 7T Epilepsy Task Force Consensus Recommendations on the Use of 7T MRI in Clinical Practice. Neurology, 2021, 96 (7), pp.327-341. ⟨10.1212/WNL.0000000000011413⟩. ⟨hal-03501353⟩
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