Search - Aix-Marseille Université Access content directly

Filter your results

24 Results
authFullName_s : Gang Cheng

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism

Gang Cheng , Jacek Zielonka , Donna Mcallister , Micael Hardy , Olivier Ouari , et al.
Cancer Letters, 2015, 365 (1), pp.96 - 106. ⟨10.1016/j.canlet.2015.05.016⟩
Journal articles hal-01414616v1
Image document

Mitochondria-targeted hydroxyurea inhibits OXPHOS and induces antiproliferative and immunomodulatory effects

Gang Cheng , Micael Hardy , Paytsar Topchyan , Ryan Zander , Peter Volberding , et al.
Journal articles hal-03627839v1
Image document

Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation

Gang Cheng , Micael Hardy , Ming You , Balaraman Kalyanaraman
Scientific Reports, 2022, 12 (1), pp.5143. ⟨10.1038/s41598-022-08984-6⟩
Journal articles hal-04114888v1

Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases

Jacek Zielonka , Micael Hardy , Radoslaw Michalski , Adam Sikora , Monika Zielonka , et al.
Cell Biochemistry and Biophysics, 2017, 75 (3-4), pp.335--349. ⟨10.1007/s12013-017-0813-6⟩
Journal articles hal-01774183v1

Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Adam Sikora , et al.
Cell Biochemistry and Biophysics, 2017, 75 (3-4), pp.311--317. ⟨10.1007/s12013-017-0796-3⟩
Journal articles hal-01774204v1

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators.

Gang Cheng , Jacek Zielonka , Micael Hardy , Olivier Ouari , Christopher R. Chitambar , et al.
Oncotarget, 2019, 10 (37), pp.3518--3532. ⟨10.18632/oncotarget.26943⟩
Journal articles hal-02491548v1

Mito-honokiol compounds and methods of synthesis and use thereof

B. Kalyanaraman , Jacek Zielonka , Gang Cheng , Micael Hardy , Olivier Ouari , et al.
United States, Patent n° : US 20210070787 A1 20210311. 2021
Patents hal-03627816v1

Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Adam Sikora , et al.
Interface Focus, 2017, 7 (2), pp.20160109. ⟨10.1098/rsfs.2016.0109⟩
Journal articles hal-01774201v1
Image document

Polyphenolic Boronates Inhibit Tumor Cell Proliferation: Potential Mitigators of Oxidants in the Tumor Microenvironment

Gang Cheng , Hakim Karoui , Micael Hardy , Balaraman Kalyanaraman
Cancers, 2023, 15 (4), pp.1089. ⟨10.3390/cancers15041089⟩
Journal articles hal-04114827v1

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells

Gang Cheng , Jacek Zielonka , Olivier Ouari , Marcos Lopez , Donna Mcallister , et al.
Cancer Research, 2016, 76 (13), pp.3904--3915. ⟨10.1158/0008-5472.CAN-15-2534⟩
Journal articles hal-01460665v1

High-Throughput Screening of NOX Inhibitors.

Jacek Zielonka , Monika Zielonka , Gang Cheng , Micael Hardy , Balaraman Kalyanaraman
Methods in Molecular Biology, 2019, 1982, pp.429--446. ⟨10.1007/978-1-4939-9424-3_25⟩
Journal articles hal-02491524v1

Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis

Gang Cheng , Qi Zhang , Jing Pan , Yongik Lee , Olivier Ouari , et al.
Nature Communications, 2019, 10, pp.2205. ⟨10.1038/s41467-019-10042-1⟩
Journal articles hal-02491552v1
Image document

Therapeutic Targeting of Tumor Cells and Tumor Immune Microenvironment Vulnerabilities

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy
Frontiers in Oncology, 2022, 12, pp.816504. ⟨10.3389/fonc.2022.816504⟩
Journal articles hal-04114941v1

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

Jacek Zielonka , Joy Joseph , Adam Sikora , Micael Hardy , Olivier Ouari , et al.
Chemical Reviews, 2017, 117 (15), pp.10043--10120. ⟨10.1021/acs.chemrev.7b00042⟩
Journal articles hal-01774202v1
Image document

Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation

Jacek Zielonka , Monika Zielonka , Lynn Verplank , Gang Cheng , Micael Hardy , et al.
Journal of Biological Chemistry, 2016, 291, pp.7029-7044. ⟨10.1074/jbc.M115.702787⟩
Journal articles hal-01400640v1

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Marcos Lopez , et al.
Redox Biology, 2018, 14, pp.316--327. ⟨10.1016/j.redox.2017.09.020⟩
Journal articles hal-02091918v1

Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity

Jing Pan , Yongik Lee , Gang Cheng , Jacek Zielonka , Qi Zhang , et al.
iScience, 2018, 3, pp.192--+. ⟨10.1016/j.isci.2018.04.013⟩
Journal articles hal-02091906v1
Image document

Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells

Gang Cheng , Micael Hardy , Balaraman Kalyanaraman
Scientific Reports, 2023, 13 (1), pp.7254. ⟨10.1038/s41598-023-34266-w⟩
Journal articles hal-04114801v1

Enhanced antiproliferative and antitumor immune effects of mitochondria-targeted hydroxyurea

B. Kalyanaraman , Gang Cheng , Micael Hardy
United States, Patent n° : No.63/141,802. 2021
Patents hal-03627824v1
Image document

Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

Mahmoud Abueid , Donna Mcallister , Laura Mcolash , Megan Harwig , Gang Cheng , et al.
iScience, 2021, 24 (6), pp.102653. ⟨10.1016/j.isci.2021.102653⟩
Journal articles hal-03627837v1

Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling

Balaraman Kalyanaraman , Micael Hardy , Radoslaw Podsiadly , Gang Cheng , Jacek Zielonka
Archives of Biochemistry and Biophysics, 2017, 617, pp.38--47. ⟨10.1016/⟩
Journal articles hal-01774182v1

Mitochondria-targeted atovaquone: a more potent and more effective antitumor, antimicrobial, and antimaterial drug

B. Kalyanaraman , Gang Cheng , Micael Hardy
United States, Patent n° : WO 2021081500 A1 20210429. 2021
Patents hal-03627806v1

Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future

Gang Cheng , Monika Zielonka , Brian Dranka , Suresh N. Kumar , Charles R. Myers , et al.
Journal of Biological Chemistry, 2018, 293 (26), pp.10363--10380. ⟨10.1074/jbc.RA118.003044⟩
Journal articles hal-02091896v1

Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Brian Bennett , et al.
Redox Biology, 2018, 15, pp.347--362. ⟨10.1016/j.redox.2017.12.012⟩
Journal articles hal-02091912v1