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Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism
Gang Cheng
,
Jacek Zielonka
,
Donna Mcallister
,
Micael Hardy
,
Olivier Ouari
,
et al.
Journal articles
hal-01414616v1
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Mitochondria-targeted hydroxyurea inhibits OXPHOS and induces antiproliferative and immunomodulatory effects
Gang Cheng
,
Micael Hardy
,
Paytsar Topchyan
,
Ryan Zander
,
Peter Volberding
,
et al.
Journal articles
hal-03627839v1
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Combining PEGylated mito-atovaquone with MCT and Krebs cycle redox inhibitors as a potential strategy to abrogate tumor cell proliferation
Gang Cheng
,
Micael Hardy
,
Ming You
,
Balaraman Kalyanaraman
Journal articles
hal-04114888v1
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Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases
Jacek Zielonka
,
Micael Hardy
,
Radoslaw Michalski
,
Adam Sikora
,
Monika Zielonka
,
et al.
Journal articles
hal-01774183v1
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Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies
Balaraman Kalyanaraman
,
Gang Cheng
,
Micael Hardy
,
Olivier Ouari
,
Adam Sikora
,
et al.
Journal articles
hal-01774204v1
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Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators.
Gang Cheng
,
Jacek Zielonka
,
Micael Hardy
,
Olivier Ouari
,
Christopher R. Chitambar
,
et al.
Journal articles
hal-02491548v1
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Mito-honokiol compounds and methods of synthesis and use thereof
B. Kalyanaraman
,
Jacek Zielonka
,
Gang Cheng
,
Micael Hardy
,
Olivier Ouari
,
et al.
United States, Patent n° : US 20210070787 A1 20210311. 2021
Patents
hal-03627816v1
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Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms
Balaraman Kalyanaraman
,
Gang Cheng
,
Micael Hardy
,
Olivier Ouari
,
Adam Sikora
,
et al.
Journal articles
hal-01774201v1
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Polyphenolic Boronates Inhibit Tumor Cell Proliferation: Potential Mitigators of Oxidants in the Tumor Microenvironment
Gang Cheng
,
Hakim Karoui
,
Micael Hardy
,
Balaraman Kalyanaraman
Journal articles
hal-04114827v1
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Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells
Gang Cheng
,
Jacek Zielonka
,
Olivier Ouari
,
Marcos Lopez
,
Donna Mcallister
,
et al.
Journal articles
hal-01460665v1
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High-Throughput Screening of NOX Inhibitors.
Jacek Zielonka
,
Monika Zielonka
,
Gang Cheng
,
Micael Hardy
,
Balaraman Kalyanaraman
Journal articles
hal-02491524v1
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Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis
Gang Cheng
,
Qi Zhang
,
Jing Pan
,
Yongik Lee
,
Olivier Ouari
,
et al.
Journal articles
hal-02491552v1
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Therapeutic Targeting of Tumor Cells and Tumor Immune Microenvironment Vulnerabilities
Balaraman Kalyanaraman
,
Gang Cheng
,
Micael Hardy
Journal articles
hal-04114941v1
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Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications
Jacek Zielonka
,
Joy Joseph
,
Adam Sikora
,
Micael Hardy
,
Olivier Ouari
,
et al.
Journal articles
hal-01774202v1
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Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation
Jacek Zielonka
,
Monika Zielonka
,
Lynn Verplank
,
Gang Cheng
,
Micael Hardy
,
et al.
Journal articles
hal-01400640v1
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A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds
Balaraman Kalyanaraman
,
Gang Cheng
,
Micael Hardy
,
Olivier Ouari
,
Marcos Lopez
,
et al.
Journal articles
hal-02091918v1
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Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity
Jing Pan
,
Yongik Lee
,
Gang Cheng
,
Jacek Zielonka
,
Qi Zhang
,
et al.
Journal articles
hal-02091906v1
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Antiproliferative effects of mitochondria-targeted N-acetylcysteine and analogs in cancer cells
Gang Cheng
,
Micael Hardy
,
Balaraman Kalyanaraman
Journal articles
hal-04114801v1
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Enhanced antiproliferative and antitumor immune effects of mitochondria-targeted hydroxyurea
B. Kalyanaraman
,
Gang Cheng
,
Micael Hardy
United States, Patent n° : No.63/141,802. 2021
Patents
hal-03627824v1
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Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression
Mahmoud Abueid
,
Donna Mcallister
,
Laura Mcolash
,
Megan Harwig
,
Gang Cheng
,
et al.
Journal articles
hal-03627837v1
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Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling
Balaraman Kalyanaraman
,
Micael Hardy
,
Radoslaw Podsiadly
,
Gang Cheng
,
Jacek Zielonka
Journal articles
hal-01774182v1
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Mitochondria-targeted atovaquone: a more potent and more effective antitumor, antimicrobial, and antimaterial drug
B. Kalyanaraman
,
Gang Cheng
,
Micael Hardy
United States, Patent n° : WO 2021081500 A1 20210429. 2021
Patents
hal-03627806v1
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Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future
Gang Cheng
,
Monika Zielonka
,
Brian Dranka
,
Suresh N. Kumar
,
Charles R. Myers
,
et al.
Journal articles
hal-02091896v1
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Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies
Balaraman Kalyanaraman
,
Gang Cheng
,
Micael Hardy
,
Olivier Ouari
,
Brian Bennett
,
et al.
Journal articles
hal-02091912v1
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