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authFullName_s : Jacek Zielonka

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds (vol 14C, pg 316, 2017)

Balaraman Kalyanaraman , Gang Chen , Micael Hardy , Olivier Ouari , Marcos Lopez , et al.
Redox Biology, 2018, 16, pp.426--427. ⟨10.1016/j.redox.2018.03.001⟩
Journal articles hal-02091900v1

Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases

Jacek Zielonka , Micael Hardy , Radoslaw Michalski , Adam Sikora , Monika Zielonka , et al.
Cell Biochemistry and Biophysics, 2017, 75 (3-4), pp.335--349. ⟨10.1007/s12013-017-0813-6⟩
Journal articles hal-01774183v1

Modified Metformin as a More Potent Anticancer Drug: Mitochondrial Inhibition, Redox Signaling, Antiproliferative Effects and Future EPR Studies

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Adam Sikora , et al.
Cell Biochemistry and Biophysics, 2017, 75 (3-4), pp.311--317. ⟨10.1007/s12013-017-0796-3⟩
Journal articles hal-01774204v1

Synergistic inhibition of tumor cell proliferation by metformin and mito-metformin in the presence of iron chelators.

Gang Cheng , Jacek Zielonka , Micael Hardy , Olivier Ouari , Christopher R. Chitambar , et al.
Oncotarget, 2019, 10 (37), pp.3518--3532. ⟨10.18632/oncotarget.26943⟩
Journal articles hal-02491548v1

HPLC-based monitoring of products formed from hydroethidine-based fluorogenic probes — The ultimate approach for intra- and extracellular superoxide detection

Balaraman Kalyanaraman , Brian P. Dranka , Micael Hardy , Radoslaw Michalski , Jacek Zielonka
Biochimica et Biophysica Acta (BBA) - General Subjects, 2014, 1840 (2), pp.739 - 744. ⟨10.1016/j.bbagen.2013.05.008⟩
Journal articles hal-01414361v1

Boronate Probes as Diagnostic Tools for Real Time Monitoring of Peroxynitrite and Hydroperoxides

Jacek Zielonka , Adam Sikora , Micael Hardy , Joy Joseph , Brian P. Dranka , et al.
Chemical Research in Toxicology, 2012, 25 (9), pp.1793 - 1799. ⟨10.1021/tx300164j⟩
Journal articles hal-01425058v1
Image document

Oxidation of ethidium-based probes by biological radicals: mechanism, kinetics and implications for the detection of superoxide

Radosław Michalski , David Thiebaut , Bartosz Michałowski , Mehmet M Ayhan , Micael Hardy , et al.
Scientific Reports, 2020, 10, ⟨10.1038/s41598-020-75373-2⟩
Journal articles hal-03244541v1

Mito-honokiol compounds and methods of synthesis and use thereof

B. Kalyanaraman , Jacek Zielonka , Gang Cheng , Micael Hardy , Olivier Ouari , et al.
United States, Patent n° : US 20210070787 A1 20210311. 2021
Patents hal-03627816v1

Mitochondria-targeted metformins: anti-tumour and redox signalling mechanisms

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Adam Sikora , et al.
Interface Focus, 2017, 7 (2), pp.20160109. ⟨10.1098/rsfs.2016.0109⟩
Journal articles hal-01774201v1

Mitochondria-Targeted Spin Traps: Synthesis, Superoxide Spin Trapping, and Mitochondrial Uptake

Micael Hardy , Florent Poulhés , Egon Rizzato , Antal Rockenbauer , Karol Banaszak , et al.
Chemical Research in Toxicology, 2014, 27 (7), pp.1155 - 1165. ⟨10.1021/tx500032e⟩
Journal articles hal-01414126v1

Antiproliferative effects of mitochondria-targeted cationic antioxidants and analogs: Role of mitochondrial bioenergetics and energy-sensing mechanism

Gang Cheng , Jacek Zielonka , Donna Mcallister , Micael Hardy , Olivier Ouari , et al.
Cancer Letters, 2015, 365 (1), pp.96 - 106. ⟨10.1016/j.canlet.2015.05.016⟩
Journal articles hal-01414616v1

Spin trapping

Jacek Zielonka , Micael Hardy , B. Kalyanaraman
Spin trapping, 13, royal society of chemistry, pp.482-518, 2021
Book sections hal-03627665v1

Embedding cyclic nitrone in mesoporous silica particles for EPR spin trapping of superoxide and other radicals

Eric Besson , Stéphane Gastaldi , Emily Bloch , Jacek Zielonka , Monika Zielonka , et al.
Analyst, 2019, 144 (14), pp.4194-4203. ⟨10.1039/c9an00468h⟩
Journal articles hal-02187288v1

Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells

Gang Cheng , Jacek Zielonka , Olivier Ouari , Marcos Lopez , Donna Mcallister , et al.
Cancer Research, 2016, 76 (13), pp.3904--3915. ⟨10.1158/0008-5472.CAN-15-2534⟩
Journal articles hal-01460665v1

High-Throughput Screening of NOX Inhibitors.

Jacek Zielonka , Monika Zielonka , Gang Cheng , Micael Hardy , Balaraman Kalyanaraman
Methods in Molecular Biology, 2019, 1982, pp.429--446. ⟨10.1007/978-1-4939-9424-3_25⟩
Journal articles hal-02491524v1

Targeting lonidamine to mitochondria mitigates lung tumorigenesis and brain metastasis

Gang Cheng , Qi Zhang , Jing Pan , Yongik Lee , Olivier Ouari , et al.
Nature Communications, 2019, 10, pp.2205. ⟨10.1038/s41467-019-10042-1⟩
Journal articles hal-02491552v1

Detection and Characterization of Reactive Oxygen and Nitrogen Species in Biological Systems by Monitoring Species-Specific Products

Micael Hardy , Jacek Zielonka , Hakim Karoui , Adam Sikora , Radoslaw Michalski , et al.
Antioxidants & redox signaling, 2018, ⟨10.1089/ars.2017.7398⟩
Journal articles hal-02091844v1

Hydropropidine: A novel, cell-impermeant fluorogenic probe for detecting extracellular superoxide

Radoslaw Michalski , Jacek Zielonka , Micael Hardy , Joy Joseph , Balaraman Kalyanaraman
Free Radical Biology and Medicine, 2012, 54, pp.135 - 147. ⟨10.1016/j.freeradbiomed.2012.09.018⟩
Journal articles hal-01425080v1

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

Jacek Zielonka , Joy Joseph , Adam Sikora , Micael Hardy , Olivier Ouari , et al.
Chemical Reviews, 2017, 117 (15), pp.10043--10120. ⟨10.1021/acs.chemrev.7b00042⟩
Journal articles hal-01774202v1

Toward selective detection of reactive oxygen and nitrogen species with the use of fluorogenic probes – Limitations, progress, and perspectives

Karolina Debowska , Dawid Debski , Micael Hardy , Malgorzata Jakubowska , Balaraman Kalyanaraman , et al.
Pharmacological Reports, 2015, 67 (4), pp.756 - 764. ⟨10.1016/j.pharep.2015.03.016⟩
Journal articles hal-01417961v1

Global Profiling of Reactive Oxygen and Nitrogen Species in Biological Systems HIGH-THROUGHPUT REAL-TIME ANALYSES

Jacek Zielonka , Monika Zielonka , Adam Sikora , Jan Adamus , Joy Joseph , et al.
Journal of Biological Chemistry, 2012, 287 (5), pp.2984--2995. ⟨10.1074/jbc.M111.309062⟩
Journal articles hal-01460456v1
Image document

Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation

Jacek Zielonka , Monika Zielonka , Lynn Verplank , Gang Cheng , Micael Hardy , et al.
Journal of Biological Chemistry, 2016, 291, pp.7029-7044. ⟨10.1074/jbc.M115.702787⟩
Journal articles hal-01400640v1

Identification of Peroxynitrite by Profiling Oxidation and Nitration Products from Mitochondria-Targeted Arylboronic Acid

Jacek Zielonka , A. Sikora , Radoslaw Podsiadly , Micael Hardy , B. Kalyanaraman
Identification of Peroxynitrite by Profiling Oxidation and Nitration Products from Mitochondria-Targeted Arylboronic Acid, 2275 (20), Volkmar Weissig and Marvin Edeas, Mitochondrial Medecine, Methods in Molecular Biology, pp.315-327, 2021
Book sections hal-03627767v1
Image document

Synchronous effects of targeted mitochondrial complex I inhibitors on tumor and immune cells abrogate melanoma progression

Mahmoud Abueid , Donna Mcallister , Laura Mcolash , Megan Harwig , Gang Cheng , et al.
iScience, 2021, 24 (6), pp.102653. ⟨10.1016/j.isci.2021.102653⟩
Journal articles hal-03627837v1

Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity

Jing Pan , Yongik Lee , Gang Cheng , Jacek Zielonka , Qi Zhang , et al.
iScience, 2018, 3, pp.192--+. ⟨10.1016/j.isci.2018.04.013⟩
Journal articles hal-02091906v1

A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Marcos Lopez , et al.
Redox Biology, 2018, 14, pp.316--327. ⟨10.1016/j.redox.2017.09.020⟩
Journal articles hal-02091918v1

N, N. N ', N '-tetramethylhydroethidine (TMHE) - in search for better probes for the detection of superoxide radical anion

Adam Sikora , Radoslaw Michalski , Micael Hardy , Olivier Ouari , Jan Adamus , et al.
Free Radical Biology and Medicine, 2017, 108, pp.S38--S38. ⟨10.1016/j.freeradbiomed.2017.04.146⟩
Journal articles hal-01774206v1

Recent developments in detection of superoxide radical anion and hydrogen peroxide: Opportunities, challenges, and implications in redox signaling

Balaraman Kalyanaraman , Micael Hardy , Radoslaw Podsiadly , Gang Cheng , Jacek Zielonka
Archives of Biochemistry and Biophysics, 2017, 617, pp.38--47. ⟨10.1016/j.abb.2016.08.021⟩
Journal articles hal-01774182v1

Detection of mitochondria-generated reactive oxygen species in cells using multiple probes and methods: Potentials, pitfalls, and the future

Gang Cheng , Monika Zielonka , Brian Dranka , Suresh N. Kumar , Charles R. Myers , et al.
Journal of Biological Chemistry, 2018, 293 (26), pp.10363--10380. ⟨10.1074/jbc.RA118.003044⟩
Journal articles hal-02091896v1

Teaching the basics of reactive oxygen species and their relevance to cancer biology: Mitochondrial reactive oxygen species detection, redox signaling, and targeted therapies

Balaraman Kalyanaraman , Gang Cheng , Micael Hardy , Olivier Ouari , Brian Bennett , et al.
Redox Biology, 2018, 15, pp.347--362. ⟨10.1016/j.redox.2017.12.012⟩
Journal articles hal-02091912v1