Growth hormone level at admission and its evolution during refeeding are predictive of short-term outcome in restrictive anorexia nervosa - Aix-Marseille Université Access content directly
Journal Articles British Journal of Nutrition Year : 2013

Growth hormone level at admission and its evolution during refeeding are predictive of short-term outcome in restrictive anorexia nervosa

Abstract

The growth hormone (GH)– insulin-like growth factor-1 (IGF-1) axis is dramatically altered in patients with anorexia nervosa (AN). The aim of the present study was to investigate whether GH and IGF-1 could be predictors of outcome in patients with a restrictive form of AN. Blood levels of GH, IGF-1, adipocytokines, ghrelin, insulin, glucose, and sex and thyroid hormones were measured in eleven women inpa-tients with AN and in ten healthy women controls. Three stages were compared during refeeding: admission (T0), when BMI reached 16 kg/m 2 (T1) and at discharge when BMI reached 17·5 kg/m 2 (T2). Clinical status was assessed 6 months after discharge from hospital (T3), and remission was defined by the maintenance of a BMI $ 17·5 kg/m
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hal-01307680 , version 1 (26-04-2016)

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Attribution - NonCommercial - NoDerivatives

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Jp Nogueira, René Valéro, Marie Maraninchi, Anne Marie Lorec, Catherine Samuelian-Massat, et al.. Growth hormone level at admission and its evolution during refeeding are predictive of short-term outcome in restrictive anorexia nervosa. British Journal of Nutrition, 2013, 109 (12), pp.2175 - 2181. ⟨10.1017/S000711451200431X⟩. ⟨hal-01307680⟩
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