Similarity in Neuronal Firing Regimes across Mammalian Species
Yasuhiro Mochizuki
(1)
,
Tomokatsu Onaga
(1)
,
Hideaki Shimazaki
(2)
,
Takeaki Shimokawa
(3)
,
Yasuhiro Tsubo
(2, 4)
,
Rie Kimura
(5)
,
Akiko Saiki
(5)
,
Yutaka Sakai
(5)
,
Yoshikazu Isomura
(5)
,
Shigeyoshi Fujisawa
(2)
,
Ken-Ishi Shibata
(1, 6)
,
Daichi Hirai
(1, 6)
,
Takahiro Furuta
(1, 6)
,
Takeshi Keneko
(1, 5)
,
Susumu Takahashi
(7)
,
Tomaoki Nakazono
(7)
,
Seiya Ishino
(8)
,
Yoshio Sakurai
(7)
,
Takashi Kitsukawa
(9)
,
Jong Won Lee
(10)
,
Huynjung Lee
(11)
,
Min Whan Jung
(12, 10)
,
Cecilia Babul
(13)
,
Pedro E. Maldonado
(13)
,
Kazutaka Takahashi
(14, 15)
,
Fritzie I. Arce-Macshane
(15)
,
Callum F. Ross
(15, 14)
,
Barry J.Sessle
(15, 14)
,
Nicolas G. Hatsopoulos
(15)
,
Thomas Brochier
(16)
,
Alexa Riehle
(17, 16)
,
Paul Chorley
(17)
,
Sonja Grün
(2, 17)
,
Hisao Nishijo
(18)
,
Satoe Ichihara - Takeda
(19)
,
Shinraro Funahashi
(20)
,
Keisetsu Shima
(21)
,
Hajima Mushiake
(21)
,
Yukako Yamane
(22, 9)
,
Hiroshi Tamura
(23)
,
Ishiro Fujita
(22)
,
Naoko Inaba
(6)
,
Kenji Kawano
(6)
,
Sergei Kurkin
(24)
,
Kikuro Fukushima
(24)
,
Kurata Kiyoshi
(25)
,
Masato Taira
(26)
,
Ken-Ichiro Tsutsui
(27)
,
Tadashi Ogawa
(28)
,
Komatsu Hidehiko
(3)
,
Kowa Koida
(23)
,
Keisuke Toyama
(3)
,
Barry J. Richmond
(29, 30)
,
Shigeru Shinomoto
(1)
1
Kyoto University
2 RIKEN CBS - RIKEN Center for Brain Science [Wako]
3 ATR - Neural Information Analysis Laboratories
4 Intelligent Computer Entertainment Laboratory Department of Human and Computer Intelligence
5 Brain Science Institute
6 Kokoro Research Center
7 Doshisha University [Kyoto]
8 Department of Bioscience and Biotechnology [Fukuoka]
9 Department of Frontier Biosciences
10 CSBD - Center for Synaptic Brain Dysfunctions
11 KNU - Kyungpook National University [Daegu]
12 KAIST - Korea Advanced Institute of Science and Technology
13 Biomedical Neuroscience Institute
14 University of Chicago
15 Department of Organismal Biology and Anatomy
16 INT - Institut de Neurosciences de la Timone
17 INM-1 - Institute of Neuroscience and Medicine [Jülich]
18 University of Toyama
19 Sapporo Medical University
20 High energy accelerator research organization - KEK
21 Tohoku University School of Medicine
22 Osaka University [Osaka]
23 Tohoku University [Sendai]
24 Hokkaido University [Sapporo, Japan]
25 Hirosaki University
26 Tokyo Medical and Dental University
27 Department of Biology
28 National Institute for Physiological Sciences
29 NIH - National Institutes of Health [Bethesda, MD, USA]
30 Department of Combinatorics and Optimization
2 RIKEN CBS - RIKEN Center for Brain Science [Wako]
3 ATR - Neural Information Analysis Laboratories
4 Intelligent Computer Entertainment Laboratory Department of Human and Computer Intelligence
5 Brain Science Institute
6 Kokoro Research Center
7 Doshisha University [Kyoto]
8 Department of Bioscience and Biotechnology [Fukuoka]
9 Department of Frontier Biosciences
10 CSBD - Center for Synaptic Brain Dysfunctions
11 KNU - Kyungpook National University [Daegu]
12 KAIST - Korea Advanced Institute of Science and Technology
13 Biomedical Neuroscience Institute
14 University of Chicago
15 Department of Organismal Biology and Anatomy
16 INT - Institut de Neurosciences de la Timone
17 INM-1 - Institute of Neuroscience and Medicine [Jülich]
18 University of Toyama
19 Sapporo Medical University
20 High energy accelerator research organization - KEK
21 Tohoku University School of Medicine
22 Osaka University [Osaka]
23 Tohoku University [Sendai]
24 Hokkaido University [Sapporo, Japan]
25 Hirosaki University
26 Tokyo Medical and Dental University
27 Department of Biology
28 National Institute for Physiological Sciences
29 NIH - National Institutes of Health [Bethesda, MD, USA]
30 Department of Combinatorics and Optimization
Alexa Riehle
- Fonction : Auteur
- PersonId : 781052
- ORCID : 0000-0001-5890-3999
Sonja Grün
- Fonction : Auteur
- PersonId : 781053
- ORCID : 0000-0003-2829-2220
Résumé
The architectonic subdivisions of the brain are believed to be functional modules, each processing parts of global functions. Previously, we showed that neurons in different regions operate in different firing regimes in monkeys. It is possible that firing regimes reflect differences in underlying information processing, and consequently the firing regimes in homologous regions across animal species might be similar. We analyzed neuronal spike trains recorded from behaving mice, rats, cats, and monkeys. The firing regularity differed systematically, with differences across regions in one species being greater than the differences in similar areas across species. Neuronal firing was consistently most regular in motor areas, nearly random in visual and prefrontal/medial prefrontal cortical areas, and bursting in the hippocampus in all animals examined. This suggests that firing regularity (or irregularity) plays a key role in neural computation in each functional subdivision, depending on the types of information being carried. By analyzing neuronal spike trains recorded from mice, rats, cats, and monkeys, we found that different brain regions have intrinsically different firing regimes that are more similar in homologous areas across species than across areas in one species. Because different regions in the brain are specialized for different functions, the present finding suggests that the different activity regimes of neurons are important for supporting different functions, so that appropriate neuronal codes can be used for different modalities.
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