Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass - Aix-Marseille Université Access content directly
Journal Articles European Journal of Anaesthesiology Year : 2018

Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass

David Lagier
  • Function : Author
Laetitia Nee
  • Function : Author
Alexis Theron
Dominique Grisoli
  • Function : Author
Lionel Velly
Catherine Guidon
  • Function : Author

Abstract

BACKGROUND Raised plasma levels of endogenous aden-osine after cardiac surgery using cardiopulmonary bypass (CPB) have been related to the incidence of postoperative atrial fibrillation (POAF). OBJECTIVE We wished to assess if caffeine, an adenosine receptor antagonist could have a beneficial effect on the incidence of POAF. DESIGN A randomised controlled study. SETTING Single University Hospital. PATIENTS One hundred and ten patients scheduled for heart valve surgery with CPB.
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Dates and versions

hal-01788059 , version 1 (14-01-2019)

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David Lagier, Laetitia Nee, Régis Guieu, François Kerbaul, Emmanuel Fenouillet, et al.. Peri-operative oral caffeine does not prevent postoperative atrial fibrillation after heart valve surgery with cardiopulmonary bypass. European Journal of Anaesthesiology, 2018, ⟨10.1097/EJA.0000000000000824⟩. ⟨hal-01788059⟩
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