Lower Pregnancy Rates After IVF in Women Working as Occupational Cleaners A Preliminary Longitudinal Study - Aix-Marseille Université Access content directly
Journal Articles Journal of Reproductive Medicine -Chicago- Year : 2018

Lower Pregnancy Rates After IVF in Women Working as Occupational Cleaners A Preliminary Longitudinal Study

Abstract

OBJECTIVE: To assess clinical, biological, and environ­ mental factors influencing pregnancy rates (PRs) after in vitro fertilization (IVF), and to study the influence of occupational, lifestyle, and domestic exposure on PR. STUDY DESIGN: A longi­ tudinal cohort study was performed in women who started an IVF cycle with a self­administered question­ naire concerning their envi­ ronmental and occupation­ al exposure. Medical data were obtained from medical files. RESULTS: Among 534 cycles, we showed a variety of factors that had an impact on PR: age, infertility du­ ration, number of mature oocytes and embryos. After multivariate analysis, women with "elementary" occu­ pations had a significantly lower PR (OR 5.6; 95% CI 1.3-23.7). Among them, 82% were cleaners. CONCLUSION: This preliminary result leads us to focus on a socio­professional category that is already rec­ ognized in the literature as at risk for congenital abnor­ malities during pregnancy. Further cohort studies are needed to study the influence of socio­professional cate­ gory on PR.
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Dates and versions

hal-02091611 , version 1 (05-04-2019)

Identifiers

  • HAL Id : hal-02091611 , version 1

Cite

Sabrina Soen, Jeanne Perrin, Irène Sari-Minodier, Elisabeth Jouve, Audrey Gnisci, et al.. Lower Pregnancy Rates After IVF in Women Working as Occupational Cleaners A Preliminary Longitudinal Study. Journal of Reproductive Medicine -Chicago-, 2018. ⟨hal-02091611⟩
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