Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit[n]uril (n=7, 8) - Aix-Marseille Université Access content directly
Journal Articles Journal of Organic Chemistry Year : 2018

Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit[n]uril (n=7, 8)

Abstract

This is the first time that cucurbit[7]uril and cucurbit[8]uril have been demonstrated to serve as synthetic receptors for a halonium guest species, diphenyleneiodonium, modulating its bioactivities and alleviating its cardiotoxicity, which further expands the onium family of guest molecules for the cucurbit[n]uril family and provides new insights for halonium-cucurbit[n]uril host-guest chemistry and its potential applications in pharmaceutical chemistry.
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Dates and versions

hal-02091914 , version 1 (06-04-2019)

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Hang Yin, Qiaoxian Huang, Wenwen Zhao, David Bardelang, Didier Siri, et al.. Supramolecular Encapsulation and Bioactivity Modulation of a Halonium Ion by Cucurbit[n]uril (n=7, 8). Journal of Organic Chemistry, 2018, 83 (8), pp.4882--4887. ⟨10.1021/acs.joc.8b00543⟩. ⟨hal-02091914⟩
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