Current situation of malaria in the world. In 2016, 216 million indigenous malaria cases were estimated in the world. Most of them were in Africa -90%-, followed by South-East Asia -7%- and Eastern Mediterranean Region. Almost half of the world population remains at risk of malaria in 2016. Of the 91 countries reporting indigenous malaria cases, 15 countries carried 80% of the global malaria burden. In 2016, 445 000 malaria deaths were estimated worldwide, and 91% were in Africa. Almost 66% of these deaths involved children under five year-old, a population that is particularly vulnerable to this disease. Despite significant funding for malaria control in 2015, the number of indigenous malaria cases has progressively increased since 2013 after a significant decrease between 2000 and 2013 and the number of malaria-related deaths has stagnated since 2015. Emergence of resistance to most antimalarial drugs used in prevention or treatment has been observed. Malaria control and elimination require sustained long-term efforts.