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Journal Articles Open Forum Infectious Diseases Year : 2019

Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis

Abstract

A patient with multiple sclerosis presented with seronegative C. burnetii endocarditis diagnosed using C. burnetii–specific polymerase chain reaction and fluorescence in situ hybridization on cardiovascular biopsy. This case supports the necessity of a systematic polymerase chain reaction testing of removed cardiac valves because blood culture–negative endocarditis can be pauci-symptomatic, and serological tests can be negative in cases of immunosuppression.
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hal-02466925 , version 1 (05-07-2023)

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Attribution - NonCommercial - NoDerivatives

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Clea Melenotte, Ahmed Loukil, Audrey Rico, Hubert Lepidi, Didier Raoult. Blood Culture–Negative Cardiovascular Infection in a Patient With Multiple Sclerosis. Open Forum Infectious Diseases, 2019, 6 (10), ⟨10.1093/ofid/ofz429⟩. ⟨hal-02466925⟩
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