Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France - Aix-Marseille Université Access content directly
Journal Articles Acta Microbiologica et Immunologica Hungarica Year : 2021

Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France

Henriette Bosson-Vanga
Nicolas Primas
  • Function : Author
Jean-François Franetich
Catherine Lavazec
Lina Gomez
  • Function : Author
Kutub Ashraf
Maurel Tefit
  • Function : Author
Valérie Soulard
Nathalie Dereuddre-Bosquet
Roger Le Grand
Mélanie Donnette
  • Function : Author
Romain Mustière
  • Function : Author
Nadia Amanzougaghene
Shahin Tajeri
Peggy Suzanne
  • Function : Author
Aurélie Malzert-Fréon
  • Function : Author
Sylvain Rault
  • Function : Author
Patrice Vanelle
Sébastien Hutter
  • Function : Author
Anita Cohen
  • Function : Author
Georges Snounou
Pierre Roques
Nadine Azas
  • Function : Author
Prisca Lagardère
  • Function : Author
Vincent Lisowski
  • Function : Author
Nicolas Masurier
  • Function : Author
Michel Nguyen
  • Function : Author
Lucie Paloque
  • Function : Author
Françoise Benoit-Vical
Pierre Verhaeghe
Dominique Mazier

Abstract

Abstract We aimed to assess the prevalence of pathogenic bacteria and resistance genes in rectal samples collected among homeless persons in Marseille, France. In February 2014 we enrolled 114 sheltered homeless adults who completed questionnaires and had rectal samples collected. Eight types of enteric bacteria and 15 antibiotic resistance genes (ARGs) were sought by real-time polymerase chain reaction (qPCR) performed directly on rectal samples. ARG-positive samples were further tested by conventional PCR and sequencing. We evidenced a 17.5% prevalence of gastrointestinal symptoms, a 9.6% prevalence of enteric pathogenic bacteria carriage, including Escherichia coli pathotypes (8.7%) and Tropheryma whipplei (0.9%). Only 2 persons carried bla CTX-M-15 resistance genes (1.8%), while other genes, including carbapenemase-encoding genes and colistin-resistance genes, ( mcr -1 to mcr - 6, mcr-8 ) were not detected. Our results suggest that sheltered homeless persons in Marseille do not have a high risk of harbouring gastrointestinal antibiotic resistant bacteria.

Dates and versions

hal-03280482 , version 1 (09-05-2022)

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Cite

Tran Duc Anh Ly, Linda Hadjadj, van Thuan Hoang, Ndiaw Goumbala, Thi Loi Dao, et al.. Enteric pathogenic bacteria and resistance gene carriage in the homeless population in Marseille, France. Acta Microbiologica et Immunologica Hungarica, 2021, 68 (1), pp.7-13. ⟨10.1556/030.2021.01346⟩. ⟨hal-03280482⟩
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