Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest: A Systematic Review and Meta-Analysis - Aix-Marseille Université Access content directly
Journal Articles ASAIO Journal Year : 2022

Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest: A Systematic Review and Meta-Analysis

Abstract

The survival rate after cardiac arrest (CA) remains low. The utilization of extracorporeal life support is proposed to improve management. However, this resource-intensive tool is associated with complications and must be used in selected patients. We performed a meta-analysis to determine predictive factors of survival. Among the 81 studies included, involving 9256 patients, survival was 26.2% at discharge and 20.4% with a good neurologic outcome. Meta-regressions identified an association between survival at discharge and lower lactate values, intrahospital CA, and lower cardio pulmonary resuscitation (CPR) duration. After adjustment for age, intrahospital CA, and mean CPR duration, an initial shockable rhythm was the only remaining factor associated with survival to discharge (beta = 0.02, 95% CI: 0.007-0.02; p = 0.0004).

Dates and versions

hal-03792066 , version 1 (29-09-2022)

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Vassili Panagides, Marc Laine, Guillaume Fond, Guillaume Lebreton, Franck Paganelli, et al.. Survival and Factors Associated with Survival with Extracorporeal Life Support During Cardiac Arrest: A Systematic Review and Meta-Analysis. ASAIO Journal, 2022, 68 (8), pp.987-995. ⟨10.1097/MAT.0000000000001613⟩. ⟨hal-03792066⟩
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