Association of severe mental illness and septic shock case fatality rate in patients admitted to the intensive care unit: A national population-based cohort study - Aix-Marseille Université Access content directly
Journal Articles PLoS Medicine Year : 2023

Association of severe mental illness and septic shock case fatality rate in patients admitted to the intensive care unit: A national population-based cohort study

Ines Lakbar (1, 2, 3, 4, 5, 6, 7, 8) , Marc Leone (9, 10) , Vanessa Pauly (1, 2, 3, 4, 5, 6, 7, 8) , Veronica Orleans (1, 2, 3, 4, 5, 6, 7, 8) , Kossi Josue Srougbo , Sambou Diao (1, 2, 3, 4, 5, 6, 7, 8) , Pierre-Michel Llorca (7, 11) , Marco Solmi (12, 13, 14, 15) , Christoph U Correll (14, 16, 17) , Sara Fernandes (1, 2, 3, 4, 5, 6, 7, 8) , Jean-Louis Vincent (18) , Laurent Boyer (1, 2, 3, 4, 5, 6, 7, 8) , Guillaume Fond (1, 2, 3, 4, 5, 6, 7, 8)
Kossi Josue Srougbo
Jean-Louis Vincent

Abstract

Patients with severe mental illness (SMI) (i.e., schizophrenia, bipolar disorder, or major depressive disorder) have been reported to have excess mortality rates from infection compared to patients without SMI, but whether SMI is associated with higher or lower case fatality rates (CFRs) among infected patients remains unclear. The primary objective was to compare the 90-day CFR in septic shock patients with and without SMI admitted to the intensive care unit (ICU), after adjusting for social disadvantage and physical health comorbidity.
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hal-04296448 , version 1 (20-11-2023)

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Ines Lakbar, Marc Leone, Vanessa Pauly, Veronica Orleans, Kossi Josue Srougbo, et al.. Association of severe mental illness and septic shock case fatality rate in patients admitted to the intensive care unit: A national population-based cohort study. PLoS Medicine, 2023, 20, ⟨10.1371/journal.pmed.1004202⟩. ⟨hal-04296448⟩
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