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Article Dans Une Revue Current Medicinal Chemistry Année : 2023

Unlocking the Benefits of Fasting: A Review of Its Impact on Various Biological Systems and Human Health

Rawan Mackieh
  • Fonction : Auteur
Nadia Al-Bakkar
  • Fonction : Auteur
Milena Kfoury
  • Fonction : Auteur
Nathalie Okdeh
  • Fonction : Auteur
Hervé Pietra
  • Fonction : Auteur
Rabih Roufayel
  • Fonction : Auteur
Christian Legros
  • Fonction : Auteur
Ziad Fajloun
  • Fonction : Auteur
Jean-Marc Sabatier

Résumé

Abstract: Fasting has gained significant attention in recent years for its potential health benefits in various body systems. This review aims to comprehensively examine the effects of fasting on human health, specifically focusing on its impact on different body’s physiological systems. The cardiovascular system plays a vital role in maintaining overall health, and fasting has shown promising effects in improving cardiovascular health markers such as blood pressure, cholesterol levels, and triglyceride levels. Additionally, fasting has been suggested to enhance insulin sensitivity, promote weight loss, and improve metabolic health, thus offering potential benefits to individuals with diabetes and metabolic disorders. Furthermore, fasting can boost immune function, reduce inflammation, enhance autophagy, and support the body's defense against infections, cancer, and autoimmune diseases. Fasting has also demonstrated a positive effect on the brain and nervous system. It has been associated with neuroprotective properties, improving cognitive function, and reducing the risk of neurodegenerative diseases, besides the ability of increasing the lifespan. Hence, understanding the potential advantages of fasting can provide valuable insights for individuals and healthcare professionals alike in promoting health and wellbeing. The data presented here may have significant implications for the development of therapeutic approaches and interventions using fasting as a potential preventive and therapeutic strategy.
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Dates et versions

hal-04315553 , version 1 (30-11-2023)

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Citer

Rawan Mackieh, Nadia Al-Bakkar, Milena Kfoury, Nathalie Okdeh, Hervé Pietra, et al.. Unlocking the Benefits of Fasting: A Review of Its Impact on Various Biological Systems and Human Health. Current Medicinal Chemistry, 2023, 31, ⟨10.2174/0109298673275492231121062033⟩. ⟨hal-04315553⟩
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