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Article Dans Une Revue Pathogens Année : 2023

Mycobacterium tuberculosis Resides in Macrophages in Laryngeal Tuberculosis: A Case Report

Résumé

Laryngeal tuberculosis is a rare form of extrapulmonary tuberculosis that questions the natural history of this infection. We report one such case in which a pathological examination of a laryngeal biopsy revealed granulomatous inflammation with caseous necrosis. Further investigations combining immunofluorescence detection of macrophages and in situ hybridization of Mycobacterium tuberculosis indicated the presence of Mycobacterium tuberculosis (M. tuberculosis) in laryngeal granulomatous inflammatory lesions. This observation suggests that the natural history of laryngeal tuberculosis does not differ from that of other forms, guiding early diagnosis in patients with laryngeal lesions to ensure appropriate check-ups and treatment.
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hal-04509468 , version 1 (18-03-2024)

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Wafaa Achache, Mahmoud A Boualam, Nadim Cassir, Clémence Mimari, Delphine Poitrenaud, et al.. Mycobacterium tuberculosis Resides in Macrophages in Laryngeal Tuberculosis: A Case Report. Pathogens, 2023, 12 (12), pp.1413. ⟨10.3390/pathogens12121413⟩. ⟨hal-04509468⟩

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