An Analysis of Substituent Effects on the Proton and Carbon‐13 Chemical Shifts of 9‐Chloro and 9‐Amino Acridines
Résumé
Abstract The 1 H chemical shifts, 1 H‐ 1 H coupling constants, 13 C chemical shifts, and some 1 H‐ 13 C and 13 C‐ 19 F coupling constants have been determined for seven 3‐substituted‐9‐chloroacridines and for the corresponding 3‐substituted‐9‐aminoacridines. The effects produced by the substituent in position 3 on the 1 H and 13 C chemical shifts are discussed using two empirical models, those of Smith and Proulx ( F, R, Q* ) and Reynolds (σ F , σ R 0 , I, O, M).
