A unique array of neuroprotective effects of pyruvate in neuropathology - Aix-Marseille Université Access content directly
Journal Articles Frontiers in Aging Neuroscience Year : 2015

A unique array of neuroprotective effects of pyruvate in neuropathology

Abstract

The three common signature characteristics of many neurological diseases are brain hypometabolism, oxidative stress, and neuroinflammation (Melo et al., 2011; Cai et al., 2012; Heneka et al., 2014). In order to be efficient, successful treatment should target all three pathologies simultaneously. Pyruvate seems to be an ideal candidate for such a treatment because of its unique combination of neuroprotective effects (Figure 1). In this opinion paper, we attempt to review and summarize recent information concerning these effects and their significance for neuroprotection.
Fichier principal
Vignette du fichier
ptpmcrender.pdf (1.25 Mo) Télécharger le fichier
Origin Publisher files allowed on an open archive
Loading...

Dates and versions

hal-01219811 , version 1 (23-10-2015)

Identifiers

Cite

Yuri Zilberter, Olena Gubkina, Anton I. Ivanov. A unique array of neuroprotective effects of pyruvate in neuropathology. Frontiers in Aging Neuroscience, 2015, 9 (17), ⟨10.3389/fnins.2015.00017⟩. ⟨hal-01219811⟩
134 View
176 Download

Altmetric

Share

Gmail Mastodon Facebook X LinkedIn More