The Thymus-Specific Serine Protease TSSP/PRSS16 Is Crucial for the Antitumoral Role of CD4 - Aix-Marseille Université Access content directly
Journal Articles Cell Reports Year : 2015

The Thymus-Specific Serine Protease TSSP/PRSS16 Is Crucial for the Antitumoral Role of CD4

Abstract

Graphical Abstract Highlights d TSSP is an important protease for intrathymic selection of CD4 + T cells d Absence of TSSP favors both spontaneous and inflammation-induced tumor development d TSSP-dependent maturation of CD4 + T cells in the thymus is required for tumor suppression d TSSP is a thymic protease with tumor suppressor activity
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Dates and versions

hal-01230365 , version 1 (18-11-2015)

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Lydie Brisson, Laurent Pouyet, Prudence N’guessan, Stéphane Garcia, Noëlla Lopes, et al.. The Thymus-Specific Serine Protease TSSP/PRSS16 Is Crucial for the Antitumoral Role of CD4. Cell Reports, 2015, 10, pp.39-46. ⟨10.1016/j.celrep.2014.12.009⟩. ⟨hal-01230365⟩
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