Spike timing-dependent plasticity and memory
Résumé
Spike timing-dependent plasticity (STDP) is a bidirectional form of synaptic plasticity discovered about 30 years ago and based on the relative timing of pre-and post-synaptic spiking activity with a millisecond precision. STDP is thought to be involved in the formation of memory but the millisecondprecision spike-timing required for STDP is difficult to reconcile with the much slower timescales of behavioral learning. This review therefore aims to expose and discuss recent findings about i) the multiple STDP learning rules at both excitatory and inhibitory synapses in vitro, ii) the contribution of STDP-like synaptic plasticity in the formation of memory in vivo and iii) the implementation of STDP rules in artificial neural networks and memristive devices.
Mots clés
Models
Memristive devices
Synaptic plasticity STDP Hippocampus Neocortex Learning Alzheimer disease Stress disorders Development Models Memristive devices
Synaptic plasticity
STDP
Hippocampus
Neocortex
Learning
Alzheimer disease
Stress disorders
Development
synaptic plasticity STDP hippocampus neocortex learning Alzheimer disease stress disorders development models memristive devices 22 pages 112 references
synaptic plasticity
hippocampus
neocortex
learning
stress disorders
development
models
memristive devices 22 pages
112 references
Domaines
Neurosciences [q-bio.NC]| Origine | Fichiers produits par l'(les) auteur(s) |
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